Features and advantages of VHHs

• Superior biochemical and biophysical properties with high affinity and specificity, high solubility and stability, easy to handle
• Rapid tissue penetration, fast clearance
• A flexible modality, easy for genetic engineering as well as chemical modification to build multimers or multispecifics to achieve precise targeting or tunable half-life, or to be conjugated to desirable payloads including small or large molecules
• Low immunogenicity
• Easy to manufacture in microbial system with low costs